Yes, this is possible.
You will need the DuoFern-ConfigTool for this.
Set the appropriate total runtime for the actuators in each case and define a ventilation position. Each closing command, both manual and automatic, will mean lowering the shutter to this position.
Via the second closing time under step 7 of 8 you have the possibility to combine a percent position with a switching time, e.g. 100% at 22:00. The roller shutter would accordingly always close completely at 100% at 22:00.